Cultural competence is “a set of congruent behaviors, attitudes, and policies that come together in a system, agency, or among professionals and enables effective work in cross-cultural situations.”1 Cultural competence is an essential and ethical obligation for all evaluators. Applying a critical cultural lens to evaluation will ensure that efforts have cultural relevance and will generate meaningful findings that stakeholders ultimately will value and use. This Program Evaluation Tip Sheet contains tips and guiding questions aligned with the six steps of CDC’s Framework for Program Evaluation in Public Health.2